Korean Scalp Treatment · CeraXosome, developed at WELLS

Korean Scalp Treatment: CeraXosome

A Korean scalp treatment for hair that thins with age: it needs a different signal.

Dr. Won Woo Choi developed CeraXosome, a vesicle ingredient that switches the hair-growth signal back on in the follicle. He published the mechanism and presented it to hair researchers in 2026. Here you can see the lab data, the procedure and real scalp cases.

  • Experimental Dermatologymechanism published
  • WCHR 2026presented to hair researchers
  • PatentedKorea · international filed
CeraXosome vial (2.5 ml) — over 10¹⁰ CeraEV vesicles per vial
  • 10¹⁰+CeraEV vesicles in every vial
  • 112µmreached into skin
  • +40%hair-shaft growth rate
  • +30%hair-shaft thickness

In Korean · auto-subtitles available

Hair anti-aging · Video

Prevent hair aging, not just hair loss

Dr. Won Woo Choi joins Skin Master Class to talk about hair anti-aging: treating hair aging before it turns into hair loss.

  1. 01

    Hair ages before it falls

    Thickness and color change first. Hair turns finer, duller and grayer.

  2. 02

    Start at thinning, not at bald spots

    Sparse, fine or dull hair is already the signal to begin.

  3. 03

    Treat the growth signal

    CeraXosome targets Wnt/β-catenin in the dermal papilla.

See the lab evidence
Why hair thins

Two different engines behind thinning hair

Hormone-driven loss and age-related thinning start in different places. That is why medicine alone often stalls for diffuse thinning.

Androgen-driven

Where it shows
Hairline and crown, the androgen-sensitive zones
What goes wrong
DHT stalls the step from stem cell to new hair, but the stem cells stay
Response to DHT-blocking medicine
Present
What helps
DHT blockers, switching Wnt back on

Age-related

Where it shows
Spread across the whole scalp
What goes wrong
Stem cells change type and leave the follicle; the papilla runs out of cells
Response to DHT-blocking medicine
Limited
What helps
Switching Wnt back on, keeping stem cells in place

The common thread is Wnt/β-catenin, the switch that keeps a follicle in its growing phase. CeraXosome targets it directly.

The hair cycle

Every hair lives in a loop. Age shortens the growing part.

Each follicle cycles through growing, resting and shedding. Thinning happens when the growing phase gets shorter and the follicle shrinks a little with every loop.

Growing Anagen

2 – 7 years

Matrix cells around the dermal papilla divide fast and push the hair up. About 85–90% of healthy scalp hair is here.

Telogen alone lasts about three months. That is why the program is judged at around 14 weeks, not after the first session.

Inside one vial

What CeraXosome is made of

CeraEV are extracellular vesicles from a Sphingomonas ferment extract, rich in sphinganine. Their lipid makeup was measured by LC-MS/MS.

CeraXosome vial (2.5 ml) — over 10¹⁰ CeraEV vesicles per vial
CeraEVLC-MS/MS
  • 71%Dihydro-ceramide (Cer NdS)
  • 24%Ceramide (Cer NS)
  • 5%Phyto-ceramide (Cer NP)
  • 10¹⁰+CeraEV vesicles in each 2.5 mL vial
  • 122.6 nmmean vesicle size
  • 112 µmdepth reached in skin (Franz cell, 3D imaging)
Electron microscope image of CeraEV extracellular vesicles, 100 nm scale bar
CeraEV under the electron microscope
3D fluorescence image of CeraXosome vesicles penetrating skin, about 112 µm deep (Franz cell)
Vesicles reaching 112 µm into skin
How it is made
  • Precision fermentation and concentration
  • Ingredients: 100% CeraXosome
  • No petrochemicals
  • No preservatives
  • High-temperature sterilized twice
  • Suitable for men and women
  • Patented in Korea, international application filed
CeraXosome box and vials
The evidence

What the lab measured

Tests on human dermal papilla cells and on hair follicles cultured outside the body. The mechanism data were published in Experimental Dermatology.

Growth-factor mRNA in dermal papilla cellsrelative to untreated = 1
IGF-1
1Untreated
×2.30.2%
×2.90.4%
×3.90.8%
VEGF
1Untreated
×2.90.2%
×3.40.4%
×50.8%
  • ×3.9IGF-1

    Growth-factor signal rose with the dose

  • ×5.0VEGF

    The signal that feeds blood supply to the root

  • Wnt onβ-catenin · LEF1 · AXIN2

    The growth switch, stabilized via AKT/GSK3β

  • Ki-67 ↑Matrix cells

    More dividing cells around the papilla

How the signal travels
  1. CeraXosome
  2. Dermal papilla cell
  3. IGF-1 receptor
  4. PI3K / AKT
  5. GSK3β held back
  6. β-catenin stabilized
  7. LEF1/TCF genes on
  8. Matrix cells multiply
  9. Faster, thicker hair

Human hair follicles, 6 days in culture

Cultured human hair follicles after 6 days: untreated vs CeraXosome 1%
+40%Hair-shaft growth rate
Hair shaft thickness on day 0 and day 6: untreated vs CeraXosome 1%
+30%Hair-shaft thickness
Ki-67 staining of human hair follicles: untreated vs CeraXosome 0.8%
Ki-67 (red) marks dividing cells. More signal around the papilla (DP) with CeraXosome.

Published in Experimental Dermatology · Presented at the World Congress for Hair Research 2026 · Sphinganine on hair loss: Clinical, Cosmetic and Investigational Dermatology 2016

Scalp cases

Before, during and after

Real WELLS patients, photographed at each visit. Drag the line to compare, or tap a stage.

Time-lapse

Same scalp, every visit

Three patients photographed at each session. Watch the stages play, or tap one.

WELLS CeraXosome scalp program, case 1 — before treatment
WELLS CeraXosome scalp program, case 1 — after session 1
WELLS CeraXosome scalp program, case 1 — after session 3
WELLS CeraXosome scalp program, case 1 — after session 5
WELLS CeraXosome scalp program, case 7 — before treatment
WELLS CeraXosome scalp program, case 7 — after session 1
WELLS CeraXosome scalp program, case 7 — after session 3
WELLS CeraXosome scalp program, case 7 — after session 5
WELLS CeraXosome scalp program, case 8 — before treatment
WELLS CeraXosome scalp program, case 8 — after session 1
WELLS CeraXosome scalp program, case 8 — after session 3
WELLS CeraXosome scalp program, case 8 — after session 5
Before
    • WELLS CeraXosome scalp program, case 1 — after session 1
      WELLS CeraXosome scalp program, case 1 — after session 3
      WELLS CeraXosome scalp program, case 1 — after session 5
      WELLS CeraXosome scalp program, case 1 — before treatment
      BeforeSession 5
      Case 01
    • WELLS CeraXosome scalp program, case 7 — after session 1
      WELLS CeraXosome scalp program, case 7 — after session 3
      WELLS CeraXosome scalp program, case 7 — after session 5
      WELLS CeraXosome scalp program, case 7 — before treatment
      BeforeSession 5
      Case 02
    • WELLS CeraXosome scalp program, case 2 — 10 weeks later
      WELLS CeraXosome scalp program, case 2 — before treatment
      Before10 weeks
      Case 0310 weeks
    • WELLS CeraXosome scalp program, case 8 — after session 1
      WELLS CeraXosome scalp program, case 8 — after session 3
      WELLS CeraXosome scalp program, case 8 — after session 5
      WELLS CeraXosome scalp program, case 8 — before treatment
      BeforeSession 5
      Case 04
    • WELLS CeraXosome scalp program, case 6 — 10 weeks later
      WELLS CeraXosome scalp program, case 6 — before treatment
      Before10 weeks
      Case 0510 weeks
    • WELLS CeraXosome scalp program, case 9 — 12 weeks later
      WELLS CeraXosome scalp program, case 9 — before treatment
      Before12 weeks
      Case 0612 weeks
    • WELLS CeraXosome scalp program, case 3 — after session 1
      WELLS CeraXosome scalp program, case 3 — after session 5
      WELLS CeraXosome scalp program, case 3 — before treatment
      BeforeSession 5
      Case 07
    • WELLS CeraXosome scalp program, case 4 — 10 weeks later
      WELLS CeraXosome scalp program, case 4 — before treatment
      Before10 weeks
      Case 0810 weeks
    • WELLS CeraXosome scalp program, case 5 — 10 weeks later
      WELLS CeraXosome scalp program, case 5 — before treatment
      Before10 weeks
      Case 0910 weeks
    Find your stage

    Analyze your hair loss in six questions

    Built on the scales dermatologists use in clinic: Ludwig for crown thinning, Norwood-Hamilton for the hairline. Under a minute. You get a structured report and can book straight from it.

    1 / 6

    Where is it thinning?

    The 14-week program

    Measured at the start, measured at the end

    Sessions every two weeks, with photos and a scalp microbiome test before the first session and after the last.

    1. Week 0CX
    2. Week 2CX
    3. Week 4CX
    4. Week 6CX
    5. Week 8CX
    6. Week 10CX
    7. Week 12CX
    8. Week 14
    Week 0
    • Photos from 4 angles
    • Scalp microbiome test
    • First CeraXosome session
    • Daily chews begin
    Week 2 – 12

    CeraXosome session × 6

    Week 14
    • Photos from the same 4 angles
    • Microbiome re-test
    • Side-by-side review
    Dtology NMN + Phyto Spermidine + Keratin chews taken every evening during the program
    Every evening for three months

    Dtology NMN + Phyto Spermidine + Keratin chews

    • NMNEnergizes aged, shrunken follicles, improves blood flow and holds back DKK-1, a hair-loss factor.
    • SpermidineLengthens the growing (anagen) phase and wakes stem cells for new hair.
    • KeratinSupplies building blocks, especially cysteine, for stronger hair.
    In the treatment room

    Every step of a session, as it happens

    Photos from Dr. Choi’s own protocol. Nothing is hidden, from the tray to the last pass.

    Treatment tray: lidocaine spray, CeraXosome vial, 3 cc syringe, autoMTS and 5-pin scalp cartridge
    01

    The tray

    Lidocaine spray, one CeraXosome vial, a 3 cc syringe, the autoMTS handpiece and a sealed cartridge.

    Standardized scalp photograph taken at the start of the program
    02

    Four standard photos

    Front hairline, both sides and the crown, taken the same way each visit.

    Lidocaine spray applied to the hairline three minutes before treatment
    03

    Numbing spray, three minutes

    Sprayed on the hairline (and crown if treated), then a three-minute wait.

    autoMTS handpiece with needle length set under 0.25 mm
    04

    Needle under 0.25 mm

    The depth is set below 0.25 mm before the handpiece touches the scalp.

    Disposable sterile 5-pin narrow scalp cartridge
    05

    Sterile 5-pin cartridge

    A narrow scalp cartridge, disposable and opened for you.

    CeraXosome delivered along the hairline with autoMTS
    06

    Hairline first

    CeraXosome is delivered line by line along the hairline.

    CeraXosome delivered at the crown with autoMTS
    07

    Then the crown

    The same pattern across the crown.

    Coming from abroad

    Plan your Korean scalp treatment around your trip

    1. 01

      One trip

      Microbiome test, one in-clinic session and three boxes of NMN chews. That is the listed package, and home care continues for three months.

    2. 02

      Two weeks or longer in Seoul

      Sessions every two weeks, as in the clinical program. The dermatologist sets how many.

    3. 03

      Coming back regularly

      We plan the remaining sessions around your next visits to Seoul.

    Price

    What the Korean scalp treatment package includes

    CeraXosome Scalp & Hair Program

    Microbiome test + session + three boxes of NMN chewable supplements₩770,000Excludes 10% VAT
    Ask about sessions for my case
    Start before you fly

    Send four scalp photos

    The same four angles Dr. Choi uses in clinic. From them, the team can tell you which program fits.

    1. Front hairline
    2. Right hairline
    3. Left hairline
    4. Crown from above
    Send 4 photos on WhatsApp
    Dr. Won Woo Choi, board-certified dermatologist (M.D., Ph.D.), head director of WELLS Dermatology in Apgujeong, Seoul
    The doctor who made it

    The developer treats you himself

    Dr. Won Woo Choi is a board-certified dermatologist (M.D., Ph.D.). He developed CeraXosome at CutisBio and presented it at the World Congress for Hair Research 2026. He reviews your photos, plans your sessions and performs the treatment.

    • M.D., Ph.D., board-certified dermatologist
    • Developer of CeraXosome (CutisBio)
    • Speaker, World Congress for Hair Research 2026
    • Mechanism published in Experimental Dermatology
    Dr. Choi’s profile
    Questions

    Korean scalp treatment: what patients ask

    Can I keep taking my hair-loss medicine?

    Yes. CeraXosome works on the Wnt growth signal and is often combined with medicine. Bring your current prescriptions so the dermatologist can review them.

    Is it for women as well as men?

    Yes. Dr. Choi’s research lists postpartum, postmenopausal and male-pattern hair loss, and most of the cases on this page are women.

    Can I do it after a hair transplant?

    Yes. Post-transplant care is one of the listed uses, and one of the cases above started within three months of surgery.

    How many sessions will I need?

    The clinical program runs a session every two weeks for about 14 weeks. The dermatologist decides the number for you from your photos.

    Does it hurt?

    Lidocaine spray goes on three minutes before, and the needle depth stays under 0.25 mm.

    When will I see a change?

    The cases above were photographed at 10 to 15 weeks. Each case shows its own timing.

    Google reviews

    What international patients wrote

    Reviews from patients who flew in, quoted as written.

    • ★★★★★English
      I have been going to Wells Dermatology Clinic whenever I visit Seoul over 12 years. All the staffs and doctors are exceptionally friendly and very professional. I thank Dr. Choi for his exceptional care and his knowledge. My skin has been improved over the years and I will continue to go back.

      June J. · Google · 2 years ago

    • ★★★★★English
      My husband and I had various services including Ulthera and Sculptura here and we were really pleased to have tried. The Dr speaks English and was very thorough in their explanations. The staff were very good at explaining the procedure and after care. … We're very happy with the level of service and results.

      C. M. · Google · a month ago

    • ★★★★★日本語
      韓国人の知り合いの紹介でシミ取りとサーマクールを受けてきました。始めはとても緊張していましたが、院長先生もとても優しく施術中も気を遣ってくださり安心して受けることができました。病院内は清潔感があり、とても綺麗なのもポイント高いです。

      TranslationOn the recommendation of a Korean acquaintance, I had pigment-spot removal and Thermage. I was very nervous at first, but the director was very kind and attentive during the treatment, so I felt at ease. The clinic is clean and very beautiful, which is another big plus.

      Soomi K. · Google · 1 year ago

    • ★★★★★日本語
      SNSで有名な病院は回転率あげようと診察が雑な所もありますが、こちらはそのような感じが一切なく診察も医院長先生が丁寧に診てアドバイスをくれます。…日本人スタッフもいるので安心してお任せできます。

      TranslationSome clinics that are famous on social media rush consultations to increase turnover, but there's none of that here — the director examines you carefully and gives advice. … There are Japanese-speaking staff, so I can relax and leave it to them.

      miiipanda · Google · 2 years ago

    • ★★★★★日本語
      予約時から術後まで終始丁寧な対応で、当日帰国することを伝えると「買い物する時間もあるといいよね」と、時間を早めて下さいました。スタッフの方も院長先生も分かりやすく説明して下さり、こちらの希望も聞いた上でどの施術がいいか勧めて下さいました。

      TranslationFrom booking through aftercare they were attentive the whole time. When I said I was flying home that day, they moved my appointment earlier so I'd have time to shop. The staff and the director explained everything clearly and recommended a treatment after hearing what I wanted.

      Alf · Google · 3 months ago

    • ★★★★★中文
      经朋友介绍,来WELLS皮肤科做了热玛吉和超声刀,医院总体来讲,整洁安静,院长的技术也非常专业熟练,职员也比较热情,下次会介绍朋友来的。

      TranslationA friend introduced me, and I came to WELLS Dermatology for Thermage and Ultherapy. The clinic is clean and quiet, the director's technique is very professional and skilled, and the staff are warm. Next time I'll bring friends.

      Xiaoli · Google · 7 months ago

    Read all reviews on Google ↗

    From Dr. Choi’s blog

    Read more about hair loss

    All articles
    Find my stageSend 4 photos

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